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YC Therapeutics companies

64 Y Combinator companies in Therapeutics, with team size, growth, open roles and funding.

Updated weekly, last on November 9, 2026. Roster from Y Combinator's public directory.

Hiring the mostlast 60 days
3 roles
Kernal BiologicsS20
See all 1
Fastest growingteam, 6 months
+21%
Sensible BiotechnologiesS21
  1. 2Modulari-T+10%
  2. 3Kopra Bio+6%
See all 5
Shrinkingteam, 12 months
−8%
Ochre BioW20
  1. 21910−6%
See all 2
Raised the mostlast 12 months
$37M
Altay TherapeuticsW20
  1. 2Sensible Biotechnologies$20M
  2. 3ParcelBio$13M
See all 8
Companies
64
Active
53
Hiring, last 60 days
1
Open roles, 60 days
3
People on these teams
572
Showing 50 of 64 companies
CompanyBatchTeam6 mo12 moOpen rolesTotal raisedLast round
RNA medicines for liver diseases
W2059−2%−8%0$39.8MSeries A$30M, Oct 2022
Multimodal AI Platform for Modality Agnostic Drug Discovery™
W1950−2%−6%0$26.6MUndisclosed round$550K, Oct 2024
Unlocking the next generation of mRNA medicines
S2135+21%+35%0$70.9MSeries A$20M, Oct 2026
A self-help app for people to manage their ADHD.
S21Acquired30−6%−21%0$14MSeries A$11M, Jan 2023
Discovering bispecific antibody drug-conjugates (BsADC) against cancer
W2130−3%+7%0$11.9MSeed$11.8M, Oct 2025
Kernal is creating mRNA 2.0 therapies that work in specific cells
S2021+5%+40%3$73MGrant$48M, Oct 2025
AI platform accelerating therapies for rare & inflammatory diseases.
S1920+5%+18%0$22.5MUndisclosed round$5.5M, Dec 2025
mRNA therapeutics to extend healthspan entering clinical trials
S18200%0%0$23.2MUndisclosed round$2.1M, Sep 2026
Genetically engineered viruses that teach your immune system to kill…
S2418+6%+38%0$9.7MSeed$9.1M, Jun 2026
We build better immunotherapies
S1915 −6%0$218MSeries C$55M, Apr 2024
We bank your stem cells to help you live healthier, longer.
S1715 −6%0$2.6MUndisclosed round$500K, Oct 2025
Programmable DNA drug destroying all cancers, unlocking 80% of targets
X2614  0$500KYC investment$500K, Jun 2026
A nonprofit stool bank enabling access to fecal transplants.
W2013−7%+8%0$100KGrant$100K, Jan 2022
We teach your immune system to attack and cure cancer
W2311+10%+22%0$500KYC investment$500K, Apr 2023
Living therapies for pets first, and their people next
W19100%0%0$475KGrant$100K, May 2022
A platform to make artificial viruses as cancer therapeutics.
S2190%+13%0$4.1MSeed$4M, Feb 2025
Regulating the immune system to block cancer & autoimmune diseases
S2190%0%0$8.7MConvertible note$4.5M, Nov 2023
Utilizing monogenic disorders to inform and solve highly complex…
S189+13% 0$7.9MGrant$3.7M, Nov 2021
RNA intelligence for precision medicine
S258  0$7.3MSeed$7.2M, May 2026
Building programmable therapeutics for the immune system
W248+33%+33%0$7.6MSeed$7.1M, Jul 2024
Cell-specific genetic medicines
W2180%−33%0$125KYC investment$125K, Jan 2023
Human whole body end-of-life preservation for later revival.
W188  0$120KUndisclosed round$120K, Jan 2021
Elevated mRNA for transformative medicines.
W2470%+17%0$13.5MSeed$13M, May 2026
Oral drugs to halt neurodegeneration
W227+40%+40%0Undisclosed roundMar 2022
Altay develops disease-modifying therapies targeting transcription…
W207+17%+40%0$40.2MSeries A$37M, Oct 2026
Smart gels for local drug delivery to the gut
W197+17%+17%0$645KSeries A$250K, Nov 2021
YourChoice therapeutics is revolutionizing the contraceptive market…
W1970%+17%0$17.2MUndisclosed round$500K, Jan 2025
Our drugs engage the immune system to fight tumors
W246−14%−14%0$500KYC investment$500K, Feb 2024
Combinations therapy by rational design
S226  0$650KUndisclosed round$150K, Nov 2023
Targeting the Tumor Ecosystem to address cancer drug resistance.
W2260%0%0$2.3MSeed$1.8M, Oct 2024
Cloud AI microscopy automation
W216+20%−33%YC$2.1MSeed$2.1M, Jan 2022
Curative genetic medicines for kidney diseases
S2060%0%0$20KSeed$20K, Oct 2026
We are developing a drug to burn calories and increase metabolism…
W2060%0%0$650KUndisclosed round$500K, Jan 2022
Sigma Genetics is a biotechnology company that is building…
W176  0Non-equity supportMar 2026
Making Next-Generation Antibiotics that Outpace Bacterial Evolution
S2450%0%0$500KYC investment$500K, Sep 2024
Breakthrough medicines unlocking the biology of heme
W2450%0%0$500KYC investment$500K, Feb 2024
Platform injectable gel based therapeutic for osteoarthritis
S225  0$5.4MGrant$4.9M, Nov 2024
Precision-first therapies
W19Inactive50%0%0$64MSeries A$52M, Jun 2022
Extrapolative AI to unlock First-in-Class drugs
S264  0
Potent, durable, and redosable non-viral genetic medicines
W22Acquired4−64%−60%0$3.9MSeed$3.9M, May 2022
A therapeutics platform for curing inflammatory disorders
S214 −20%0$125KSeed$125K, Feb 2025
The cure for hair loss.
S18Inactive4  0$2.7MSeed$2.7M, Jan 2022
Tradewind translates scientific insight into innovative ways of…
W184−20%−20%0$120KYC investment$120K, Jan 2018
Engineering next-generation, brain-penetrant cancer therapies.
W18Inactive4  0$25MSeries A$25M, Feb 2021
Engineering the future of Cancer Drug Discovery
F263  0
A Disease Focused Biotech, Building Multiple Billion Dollar Drugs
W253  0$500KYC investment$500K, Mar 2025
Redefining the Standard of Care for Iron Deficiency Anemia
S223  0Pre-seedAug 2022
Enabling Tissue Targeting of Therapies
S223  0$500KYC investment$500K, Sep 2022
W193  0$15MSeed$4M, Aug 2023
Replacing organ transplant with an infusion
S183  0$4.4MGrant$770K, May 2025

How this works

1. The roster

Every launched company in YC's public directory, with its batch, status, industry and location. New companies show up the week YC lists them.

2. The numbers

Each company is matched to Crustdata by its website. Crustdata adds team size and its change over 6 and 12 months, open roles from job postings, reported funding, and founders' past employers.

3. The lists

Hiring the most counts distinct roles posted in the last 60 days. Growth needs 10+ people today, shrinking 20+ a year ago, so tiny teams do not top the lists. Rebuilt every week.

Built with Crustdata. Get your own API key and build your own.

The numbers on this page come from three Crustdata API calls. Crustdata tags 5,000+ companies with Y Combinator as an investor; swap the filter for any investor, industry or headcount range and track your own list, with founders' work emails one call away.

  • Company search for team size, growth and funding
  • Job search with a count by company, for who is hiring and for what
  • A watch that re-runs the search weekly and sends only what changed
# 1. every company with Y Combinator as an investor
curl https://api.crustdata.com/company/search \
  -H "authorization: Bearer $CRUSTDATA_API_KEY" \
  -H "x-api-version: 2025-11-01" \
  -d '{
    "filters": { "field": "funding.investors",
                 "type": "in", "value": ["Y Combinator"] },
    "fields": ["basic_info.name",
      "headcount.total", "headcount.growth_percent",
      "funding.total_investment_usd"],
    "limit": 100
  }'

# 2. open listings per company, last 60 days (limit 0 = counts only)
curl https://api.crustdata.com/job/search \
  -H "authorization: Bearer $CRUSTDATA_API_KEY" \
  -H "x-api-version: 2025-11-01" \
  -d '{
  "filters": { "op": "and", "conditions": [
    { "field": "company.basic_info.company_id",
      "type": "in", "value": [...] },
    { "field": "metadata.date_added",
      "type": "=>", "value": "2026-08-24" } ]},
  "limit": 0,
  "aggregations": [{ "type": "group_by",
    "field": "company.basic_info.company_id", "agg": "count" }]
}'

# 3. the same company filter as a weekly watch: POST /watch/company/search

Questions about YC Therapeutics companies

How many YC Therapeutics companies are there?

64 Y Combinator companies are in Therapeutics; 53 are active.

Which YC Therapeutics companies are hiring?

1 companies posted roles in the last 60 days, led by Kernal Biologics (3 roles). 1 mark themselves as hiring on YC's directory.

Which YC Therapeutics companies are growing fastest?

By team growth over 6 months (10+ people): Sensible Biotechnologies (+21%), Modulari-T (+10%) and Kopra Bio (+6%).

Which YC Therapeutics companies raised the most?

Largest latest rounds in the last 12 months, after their YC batch: Altay Therapeutics ($37M), Sensible Biotechnologies ($20M) and ParcelBio ($13M).

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